EST Pipeline System: Detailed and Automated EST Data Processing and Mining
نویسندگان
چکیده
Expressed sequence tags (ESTs) are widely used in gene survey research these years. The EST Pipeline System, software developed by Hangzhou Genomics Institute (HGI), can automatically analyze different scalar EST sequences by suitable methods. All the analysis reports, including those of vector masking, sequence assembly, gene annotation, Gene Ontology classification, and some other analyses, can be browsed and searched as well as downloaded in the Excel format from the web interface, saving research efforts from routine data processing for biological rules embedded in the data.
منابع مشابه
ESMP: A high-throughput computational pipeline for mining SSR markers from ESTs
UNLABELLED With the advent of high-throughput sequencing technology, sequences from many genomes are being deposited to public databases at a brisk rate. Open access to large amount of expressed sequence tag (EST) data in the public databases has provided a powerful platform for simple sequence repeat (SSR) development in species where sequence information is not available. SSRs are markers of ...
متن کاملMeeting Highlights: Joint Cold Spring Harbor Laboratory and Wellcome Trust Conference – Genome Informatics
Ewan Birney (EBI, UK) opened the meeting with a presentation on the Ensembl gene building system (http://www.ensembl.org). The first part of the process is Exonerate (Guy Slater), this is the ‘basic guts’ of BLAST, allows multiplexing and makes a lazy evaluation of the path between HSPs, to rapidly build gapped alignments. This was designed for ESTs, but is now being applied to mouse whole geno...
متن کاملOrthoSelect: a web server for selecting orthologous gene alignments from EST sequences
In the absence of whole genome sequences for many organisms, the use of expressed sequence tags (EST) offers an affordable approach for researchers conducting phylogenetic analyses to gain insight about the evolutionary history of organisms. Reliable alignments for phylogenomic analyses are based on orthologous gene sequences from different taxa. So far, researchers have not sufficiently tackle...
متن کاملESTAP-an automated system for the analysis of EST data
The EST Analysis Pipeline (ESTAP) is a set of analytical procedures that automatically verify, cleanse, store and analyze ESTs generated on high-throughput platforms. It uses a relational database to store sequence data and analysis results, which facilitates both the search for specific information and statistical analysis. ESTAP provides for easy viewing of the original and cleansed data, as ...
متن کاملInstructors and Learners’ Attitudes about English for Science and Technology: Learning and Target Needs of Mechanical Engineering Students
The current investigation sought to examine the learning and target needs of mechanical engineering (ME) students based on the learners and instructors’ attitudes though an explanatory mixed-method design. To elicit learners’ perceptions of English for Science and Technology (EST), 114 ME undergraduate students and 13 EST instructors from four Iranian state universities took part in a large qua...
متن کامل